Profile

Dr Dave Ferrier

Dr Dave Ferrier
Reader in Biology and Deputy Director of the Scottish Oceans Institute


 

Research Overview. We aim to understand how the diversity of form in the animal kingdom evolved. The focus of our research is the connection between the evolution of animal genome organisation and development, with a particular concentration on the homeobox-containing genes. The Hox gene cluster is established as a corner-stone of Evolutionary Developmental Biology, but much about the evolution of its organisation and mode of operation remains unknown. Also the Hox cluster is not unique as a homeobox gene cluster controlling animal development, further clusters being the ParaHox and NK clusters, all of which evolved within larger arrays of homeobox genes (the Mega-cluster, Giga-cluster and Super-Hox cluster). We utilize a variety of organisms in our research (including amphioxus, sea squirts, polychaetes and priapulids), chosen from key points in the phylogeny of the animals to enable reconstruction of the ancestral conditions at major nodes in the animal kingdom; the origin of bilaterians, protostomes, deuterostomes, chordates and vertebrates, as well as the origin of the entire animal kingdom. Knowledge of such ancestors is vital in understanding subsequent diversification.

source: symbiosis

 

8 (of 8 published available) for dekf with keyword CLUSTER clear keyword filter. (source: University of St Andrews PURE)
Please click title of any item for full details

Amphioxus SYCP1 David Ellard Keith Ferrier
Development Genes and Evolution 2018 vol.228 pp.13-30
Two more Posterior Hox genes and Hox cluster dispersal in echinoderms David Ellard Keith Ferrier
BMC Evolutionary Biology 2018 vol.18
Evolution of homeobox gene clusters in animals David Ellard Keith Ferrier
Frontiers in Ecology and Evolution 2016 vol.4
Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes Sofia Fortunato, Marcin Adamski, Sven Leininger, Jing Liu, David Ellard Keith Ferrier, Maja Adamska
Nature 2014 vol.514 pp.620-623
The First Myriapod Genome Sequence Reveals Conservative Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima Ariel D Chipman, David Ellard Keith Ferrier, Carlo Brena, Jiaxin Qu, Daniel S T Hughes, Reinhard Schröder, Montserrat Torres-Oliva, Nadia Znassi, Huaiyang Jiang, Francisca C Almeida, Claudio R Alonso, Zivkos Apostolou, Peshtewani Aqrawi, Wallace Arthur, Jennifer C J Barna, Kerstin P Blankenburg, Daniela Brites, Salvador Capella-Gutiérrez, Marcus Coyle, Peter K Dearden, Louis Du Pasquier, Elizabeth J Duncan, Dieter Ebert, Cornelius Eibner, Galina Erikson, Cassandra G Extavour, Liezl Francisco, Toni Gabaldón, William J Gillis, Elizabeth A Goodwin-Horn, Jack E Green, Sam Griffiths-Jones, Cornelis J P Grimmelikhuijzen, Sai Gubbala, Roderic Guigó, Yi Han, Frank Hauser, Paul Havlak, Luke Hayden, Sophie Helbing, Michael Holder, Jerome H L Hui, Julia P Hunn, Vera S Hunnekuhl, LaRonda Jackson, Mehwish Javaid, Shalini N Jhangiani, Francis M Jiggins, Tamsin E Jones, Tobias S Kaiser, Divya Kalra, Nathan J Kenny, Viktoriya Korchina, Christie L Kovar, F Bernhard Kraus, François Lapraz, Sandra L Lee, Jie Lv, Christigale Mandapat, Gerard Manning, Marco Mariotti, Robert Mata, Tittu Mathew, Tobias Neumann, Irene Newsham, Dinh N Ngo, Maria Ninova, Geoffrey Okwuonu, Fiona Ongeri, William J Palmer, Shobha Patil, Pedro Patraquim, Christopher Pham, Ling-Ling Pu, Nicholas H Putman, Catherine Rabouille, Adelaide C Rhodes, Helen E Robertson, Hugh M Robertson, Matthew Ronshaugen, Julio Rozas, Nehad Saada, Alejandro Sánchez-Gracia, Steven E Scherer, Andrew M Schurko, Kenneth W Siggens, DeNard Simmons, Anna Stief, Eckart Stolle, Maximilian J Telford, Kristin Tessmar-Raible, Rebecca Thornton, Maurijn van der Zee, Arndt von Haeseler, James M Williams, Judith H Willis, Yuanqing Wu, Xiaoyan Zou, Daniel Lawson, Donna M Muzny, Kim C Worley, Richard A Gibbs, Michael Akam, Stephen Richards
PLoS Biology 2014 vol.12
Time is of the essence for ParaHox homeobox gene clustering. David Ellard Keith Ferrier
BMC Biology 2013 vol.11
An EST screen from the annelid Pomatoceros lamarckii reveals patterns of gene loss and gain in animals. T. Takahashi, C. McDougall, J. Troschianko, W-C. Chen, A.J. Nagarajan, S.M. Shimeld, David Ellard Keith Ferrier
BMC Evolutionary Biology 2009 vol.9
Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes JHL Hui, F Raible, N Korchagina, N Dray, S Samain, G Magdelenat, C Jubin, B Segurens, G Balavoine, D Arendt, David Ellard Keith Ferrier
BMC Biology 2009 vol.7

Contact

The Secretary
Scottish Oceans Institute
Institiud Chuantan na h-Alba
Gatty Marine Laboratory
East Sands St Andrews
KY16 8LB
Scotland
UK

tel: +44 (0) 1334 463472
fax: +44 (0) 1334 463443
email: soi@st-andrews.ac.uk

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