Dr Dave Ferrier

Dr Dave Ferrier
Reader in Biology and Deputy Director of the Scottish Oceans Institute


Research Overview. We aim to understand how the diversity of form in the animal kingdom evolved. The focus of our research is the connection between the evolution of animal genome organisation and development, with a particular concentration on the homeobox-containing genes. The Hox gene cluster is established as a corner-stone of Evolutionary Developmental Biology, but much about the evolution of its organisation and mode of operation remains unknown. Also the Hox cluster is not unique as a homeobox gene cluster controlling animal development, further clusters being the ParaHox and NK clusters, all of which evolved within larger arrays of homeobox genes (the Mega-cluster, Giga-cluster and Super-Hox cluster). We utilize a variety of organisms in our research (including amphioxus, sea squirts, polychaetes and priapulids), chosen from key points in the phylogeny of the animals to enable reconstruction of the ancestral conditions at major nodes in the animal kingdom; the origin of bilaterians, protostomes, deuterostomes, chordates and vertebrates, as well as the origin of the entire animal kingdom. Knowledge of such ancestors is vital in understanding subsequent diversification.

source: symbiosis


Recent publications

16  (of 16 published available) for dekf with keyword COMPLEX clear keyword filter. (source: University of St Andrews PURE)
Please click title of any item for full details.

2018 (1)
Development Genes and Evolution
vol.228 pp.13-30
2018 (21/11)
vol.564 pp.64-70
Amphioxus functional genomics and the origins of vertebrate gene regulation
Ferdinand Marletaz, Panos Firbas, Ignacio Maeso, Juan Tena, Ozren Bogdanovic, Malcolm Perry, Chris Wyatt, Elisa de la Calle-Mustienes, Stephanie Bertrand, Demian Burguera, Rafael Acemel, Simon van Heeringen, Silvia Naranjo, Carlos Herrera-Ubeda, Ksenia Skvortsova, Sandra Jimenez-Gancedo, Daniel Aldea, Yamile Marquez, Lorena Buono, Iryna Kozmikova, Jon Permanyer, Alexandra Louis, Beatriz Albuixech-Crespo, Yann Le Petillon, Anthony Leon Florian, Lucie Subirana, Piotr J. Balwierz, Paul Duckett, Ensieh Farahani, Jean Marc Aury, Sophie Mangenot, Patrick Wincker, Ricard Albalat, Elia Benito-Gutierrez, Cristian Canestro, Filipe Castro, Salvatore D'Aniello, David Ellard Keith Ferrier, Shengfeng Huang, Vincent Laudet, Gabriel Marais, Pierre Pontarotti, Michael Schubert, Herve Seitz, Ildiko Maureen Lara Somorjai, Tokiharu Takahashi, Olivier Mirabeau, Anlong Xu, Jr-Kai Yu, Piero Carninci, Juan Martinez-Morales, Hugues Crollius, Zbynek Kozmik, Matt Weirauch, Jordi Garcia-Fernandez, Ryan Lister, Boris Lenhard, Peter Holland, Hector Escriva, Jose Luis Gomez-Skarmeta, Manuel Irimia 
2018 (6/4)
Science Advances
Light-sheet microscopy with attenuation-compensated propagation-invariant beams
Jonathan Nylk, Miguel Preciado, Michael Mazilu, Zhengyi Yang, Frank J Gunn-Moore, Javier Ananda Tello, David Ellard Keith Ferrier, Kishan Dholakia 
2018 (20/6)
Scientific Reports
Pax3/7 duplicated and diverged independently in amphioxus, the basal chordate lineage
David Ellard Keith Ferrier, Ildiko Maureen Lara Somorjai 
2017 (31/8)
(Review article)
2016 (5/9)
Briefings in Functional Genomics
vol.15 pp.333-341
(Review article)
2015 (1/8)
Biomedical Optics Express
vol.6 pp.2778-2785
Macro-optical trapping for sample confinement in light sheet microscopy
Zhengyi Yang, Peeter Piksarv, David Ellard Keith Ferrier, Frank J Gunn-Moore, Kishan Dholakia 
2015 (14/12)
Scientific Reports
Multimode fibre
Martin Plöschner, Vera Kollarova, Zbyněk Dostál, Jonathan Nylk, Thomas Barton-Owen, David Ellard Keith Ferrier, Radim Chmelík, Kishan Dholakia, Tomas Cizmar 
Keywords: Plane illumination microscopy, Optical fibers, Deep, Transmission, Beams
2014 (1/10)
Biomedical Optics Express
vol.5 pp.3434-3442
A compact Airy beam light sheet microscope with a tilted cylindrical lens
Zhengyi Yang, Martynas Prokopas, Jonathan Nylk, Frank J Gunn-Moore, David Ellard Keith Ferrier, Tom Vettenburg, Kishan Dholakia 
2014 (11)
Marine Biology
vol.161 pp.2621-2629
2014 (5)
Nature Methods
vol.11 pp.541-544
Light-sheet microscopy using an Airy beam
Tom Vettenburg, Heather Isla Campbell Dalgarno, Jonathan Nylk, Clara Coll-Lladó, David Ellard Keith Ferrier, Tomas Cizmar, Frank J Gunn-Moore, Kishan Dholakia 
2013 (12/8)
BMC Bioinformatics
Daniel Barker, David Ellard Keith Ferrier, Peter W.H. Holland, John B. O. Mitchell, Heleen Plaisier, Michael Gordon Ritchie,  
Keywords: Bioinformatics education, Teaching material, Raspberry Pi, Linux
2012 (7)
Open Biology
Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates
Michele Tinti, Catherine Johnson, Rachel Toth, David Ellard Keith Ferrier, Carol MacKintosh 
Keywords: Branchiostoma, Ciona, Hereditary spastic paraplegia, RAB3GAP1, RAB3GAP2
2011 (1/6)
Biomedical Optics Express
vol.2 pp.1564-1575
Integrated holographic system for all-optical manipulation of developing embryos
Maciej Antkowiak, Hana Cizmarova, David Ellard Keith Ferrier, Kishan Dholakia, Frank J Gunn-Moore 
Keywords: Multiphoton processes, Lasers, Ultrafast lasers
2009 (23/7)
BMC Biology
Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes
JHL Hui, F Raible, N Korchagina, N Dray, S Samain, G Magdelenat, C Jubin, B Segurens, G Balavoine, D Arendt, David Ellard Keith Ferrier 


The Secretary
Scottish Oceans Institute
Institiud Chuantan na h-Alba
Gatty Marine Laboratory
East Sands St Andrews
KY16 8LB

tel: +44 (0) 1334 463472
fax: +44 (0) 1334 463443