Profile

Dr Dave Ferrier

Dr Dave Ferrier
Reader in Biology and Deputy Director of the Scottish Oceans Institute


 

Research Overview. We aim to understand how the diversity of form in the animal kingdom evolved. The focus of our research is the connection between the evolution of animal genome organisation and development, with a particular concentration on the homeobox-containing genes. The Hox gene cluster is established as a corner-stone of Evolutionary Developmental Biology, but much about the evolution of its organisation and mode of operation remains unknown. Also the Hox cluster is not unique as a homeobox gene cluster controlling animal development, further clusters being the ParaHox and NK clusters, all of which evolved within larger arrays of homeobox genes (the Mega-cluster, Giga-cluster and Super-Hox cluster). We utilize a variety of organisms in our research (including amphioxus, sea squirts, polychaetes and priapulids), chosen from key points in the phylogeny of the animals to enable reconstruction of the ancestral conditions at major nodes in the animal kingdom; the origin of bilaterians, protostomes, deuterostomes, chordates and vertebrates, as well as the origin of the entire animal kingdom. Knowledge of such ancestors is vital in understanding subsequent diversification.

source: symbiosis

 

2 (of 2 published available) for dekf with keyword Ciona clear keyword filter. (source: University of St Andrews PURE)
Please click title of any item for full details

Transcriptional regulation of the Ciona Gsx gene in the neural plate Clare Hudson, Rosaria Esposito, Antonio Palladino, Leopoldo Staiano, David Ellard Keith Ferrier, Emmanuel Faure, Patrick Lemaire, Hitoyoshi Yasuo, Antonietta Spagnuolo
Developmental Biology 2019 vol.448 pp.88-100
Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates Michele Tinti, Catherine Johnson, Rachel Toth, David Ellard Keith Ferrier, Carol MacKintosh
Open Biology 2012 vol.2

Contact

The Secretary
Scottish Oceans Institute
Institiud Chuantan na h-Alba
Gatty Marine Laboratory
East Sands St Andrews
KY16 8LB
Scotland
UK

tel: +44 (0) 1334 463472
fax: +44 (0) 1334 463443
email: soi@st-andrews.ac.uk

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