Profile

Dr Dave Ferrier

Dr Dave Ferrier
Reader in Biology and Deputy Director of the Scottish Oceans Institute


 

Research Overview. We aim to understand how the diversity of form in the animal kingdom evolved. The focus of our research is the connection between the evolution of animal genome organisation and development, with a particular concentration on the homeobox-containing genes. The Hox gene cluster is established as a corner-stone of Evolutionary Developmental Biology, but much about the evolution of its organisation and mode of operation remains unknown. Also the Hox cluster is not unique as a homeobox gene cluster controlling animal development, further clusters being the ParaHox and NK clusters, all of which evolved within larger arrays of homeobox genes (the Mega-cluster, Giga-cluster and Super-Hox cluster). We utilize a variety of organisms in our research (including amphioxus, sea squirts, polychaetes and priapulids), chosen from key points in the phylogeny of the animals to enable reconstruction of the ancestral conditions at major nodes in the animal kingdom; the origin of bilaterians, protostomes, deuterostomes, chordates and vertebrates, as well as the origin of the entire animal kingdom. Knowledge of such ancestors is vital in understanding subsequent diversification.

source: symbiosis

 

21 (of 21 published available) for dekf with keyword EVOLUTION clear keyword filter. (source: University of St Andrews PURE)
Please click title of any item for full details

A revised spiralian homeobox gene classification incorporating new polychaete transcriptomes reveals a diverse TALE class and a divergent Hox gene Ildiko Maureen Lara Somorjai, David Ellard Keith Ferrier
Genome Biology and Evolution 2018 vol.10 pp.2151–2167
Amphioxus SYCP1 David Ellard Keith Ferrier
Development Genes and Evolution 2018 vol.228 pp.13-30
Amphioxus functional genomics and the origins of vertebrate gene regulation Ferdinand Marletaz, Panos Firbas, Ignacio Maeso, Juan Tena, Ozren Bogdanovic, Malcolm Perry, Chris Wyatt, Elisa de la Calle-Mustienes, Stephanie Bertrand, Demian Burguera, Rafael Acemel, Simon van Heeringen, Silvia Naranjo, Carlos Herrera-Ubeda, Ksenia Skvortsova, Sandra Jimenez-Gancedo, Daniel Aldea, Yamile Marquez, Lorena Buono, Iryna Kozmikova, Jon Permanyer, Alexandra Louis, Beatriz Albuixech-Crespo, Yann Le Petillon, Anthony Leon Florian, Lucie Subirana, Piotr J. Balwierz, Paul Duckett, Ensieh Farahani, Jean Marc Aury, Sophie Mangenot, Patrick Wincker, Ricard Albalat, Elia Benito-Gutierrez, Cristian Canestro, Filipe Castro, Salvatore D'Aniello, David Ellard Keith Ferrier, Shengfeng Huang, Vincent Laudet, Gabriel Marais, Pierre Pontarotti, Michael Schubert, Herve Seitz, Ildiko Maureen Lara Somorjai, Tokiharu Takahashi, Olivier Mirabeau, Anlong Xu, Jr-Kai Yu, Piero Carninci, Juan Martinez-Morales, Hugues Crollius, Zbynek Kozmik, Matt Weirauch, Jordi Garcia-Fernandez, Ryan Lister, Boris Lenhard, Peter Holland, Hector Escriva, Jose Luis Gomez-Skarmeta, Manuel Irimia
Nature 2018 vol.564 pp.64-70
Horizons in evolutionary genomics David Ellard Keith Ferrier
BMC Biology 2018 vol.16
Pax3/7 duplicated and diverged independently in amphioxus, the basal chordate lineage David Ellard Keith Ferrier, Ildiko Maureen Lara Somorjai
Scientific Reports 2018 vol.8
Two more Posterior Hox genes and Hox cluster dispersal in echinoderms David Ellard Keith Ferrier
BMC Evolutionary Biology 2018 vol.18
Recent advances in understanding the roles of whole genome duplications in evolution Carol MacKintosh, David Ellard Keith Ferrier
F1000Research 2017 vol.2017
Evolution of homeobox gene clusters in animals David Ellard Keith Ferrier
Frontiers in Ecology and Evolution 2016 vol.4
The origin of the Hox/ParaHox genes, the Ghost Locus hypothesis and the complexity of the first animal David Ellard Keith Ferrier
Briefings in Functional Genomics 2016 vol.15 pp.333-341
Cell proliferation dynamics in regeneration of the operculum head appendage in the annelid Pomatoceros lamarckii David Ellard Keith Ferrier
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 2014 vol.322B pp.257-268
The First Myriapod Genome Sequence Reveals Conservative Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima Ariel D Chipman, David Ellard Keith Ferrier, Carlo Brena, Jiaxin Qu, Daniel S T Hughes, Reinhard Schröder, Montserrat Torres-Oliva, Nadia Znassi, Huaiyang Jiang, Francisca C Almeida, Claudio R Alonso, Zivkos Apostolou, Peshtewani Aqrawi, Wallace Arthur, Jennifer C J Barna, Kerstin P Blankenburg, Daniela Brites, Salvador Capella-Gutiérrez, Marcus Coyle, Peter K Dearden, Louis Du Pasquier, Elizabeth J Duncan, Dieter Ebert, Cornelius Eibner, Galina Erikson, Cassandra G Extavour, Liezl Francisco, Toni Gabaldón, William J Gillis, Elizabeth A Goodwin-Horn, Jack E Green, Sam Griffiths-Jones, Cornelis J P Grimmelikhuijzen, Sai Gubbala, Roderic Guigó, Yi Han, Frank Hauser, Paul Havlak, Luke Hayden, Sophie Helbing, Michael Holder, Jerome H L Hui, Julia P Hunn, Vera S Hunnekuhl, LaRonda Jackson, Mehwish Javaid, Shalini N Jhangiani, Francis M Jiggins, Tamsin E Jones, Tobias S Kaiser, Divya Kalra, Nathan J Kenny, Viktoriya Korchina, Christie L Kovar, F Bernhard Kraus, François Lapraz, Sandra L Lee, Jie Lv, Christigale Mandapat, Gerard Manning, Marco Mariotti, Robert Mata, Tittu Mathew, Tobias Neumann, Irene Newsham, Dinh N Ngo, Maria Ninova, Geoffrey Okwuonu, Fiona Ongeri, William J Palmer, Shobha Patil, Pedro Patraquim, Christopher Pham, Ling-Ling Pu, Nicholas H Putman, Catherine Rabouille, Adelaide C Rhodes, Helen E Robertson, Hugh M Robertson, Matthew Ronshaugen, Julio Rozas, Nehad Saada, Alejandro Sánchez-Gracia, Steven E Scherer, Andrew M Schurko, Kenneth W Siggens, DeNard Simmons, Anna Stief, Eckart Stolle, Maximilian J Telford, Kristin Tessmar-Raible, Rebecca Thornton, Maurijn van der Zee, Arndt von Haeseler, James M Williams, Judith H Willis, Yuanqing Wu, Xiaoyan Zou, Daniel Lawson, Donna M Muzny, Kim C Worley, Richard A Gibbs, Michael Akam, Stephen Richards
PLoS Biology 2014 vol.12
The dynamics of alkaline phosphatase activity during operculum regeneration in the polychaete Pomatoceros lamarckii David Ellard Keith Ferrier
International Journal of Developmental Biology 2014 vol.58 pp.635-642
Time is of the essence for ParaHox homeobox gene clustering. David Ellard Keith Ferrier
BMC Biology 2013 vol.11
Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates Michele Tinti, Catherine Johnson, Rachel Toth, David Ellard Keith Ferrier, Carol MacKintosh
Open Biology 2012 vol.2
Annelid Distal-less/Dlx duplications reveal varied post-duplication fates Carmel McDougall, Natalia Korchagina, Johnathan Tobin, David Ellard Keith Ferrier
BMC Evolutionary Biology 2011 vol.11 pp.241
Tunicates push the limits of animal evo-devo David Ellard Keith Ferrier
BMC Biology 2011 vol.9
Ancient homeobox gene loss and the evolution of chordate brain and pharynx development Thomas Butts, Peter W.H. Holland, David Ellard Keith Ferrier
Proceedings of the Royal Society B: Biological Sciences 2010 vol.277 pp.3381-3389
An EST screen from the annelid Pomatoceros lamarckii reveals patterns of gene loss and gain in animals. T. Takahashi, C. McDougall, J. Troschianko, W-C. Chen, A.J. Nagarajan, S.M. Shimeld, David Ellard Keith Ferrier
BMC Evolutionary Biology 2009 vol.9
Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes JHL Hui, F Raible, N Korchagina, N Dray, S Samain, G Magdelenat, C Jubin, B Segurens, G Balavoine, D Arendt, David Ellard Keith Ferrier
BMC Biology 2009 vol.7

Contact

The Secretary
Scottish Oceans Institute
Institiud Chuantan na h-Alba
Gatty Marine Laboratory
East Sands St Andrews
KY16 8LB
Scotland
UK

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