Profile

Dr Dave Ferrier

Dr Dave Ferrier
Reader in Biology and Deputy Director of the Scottish Oceans Institute


 

Research Overview. We aim to understand how the diversity of form in the animal kingdom evolved. The focus of our research is the connection between the evolution of animal genome organisation and development, with a particular concentration on the homeobox-containing genes. The Hox gene cluster is established as a corner-stone of Evolutionary Developmental Biology, but much about the evolution of its organisation and mode of operation remains unknown. Also the Hox cluster is not unique as a homeobox gene cluster controlling animal development, further clusters being the ParaHox and NK clusters, all of which evolved within larger arrays of homeobox genes (the Mega-cluster, Giga-cluster and Super-Hox cluster). We utilize a variety of organisms in our research (including amphioxus, sea squirts, polychaetes and priapulids), chosen from key points in the phylogeny of the animals to enable reconstruction of the ancestral conditions at major nodes in the animal kingdom; the origin of bilaterians, protostomes, deuterostomes, chordates and vertebrates, as well as the origin of the entire animal kingdom. Knowledge of such ancestors is vital in understanding subsequent diversification.

source: symbiosis

 

Recent publications


7  (of 7 published available) for dekf with keyword Homeobox clear keyword filter. (source: University of St Andrews PURE)
Please click title of any item for full details.

2018 (1/11)
BMC Biology
vol.16 
(Article)
2016 (14/4)
Frontiers in Ecology and Evolution
vol.4 
(Review article)
2016 (5/9)
Briefings in Functional Genomics
vol.15 pp.333-341
(Review article)
2014 (30/10)
Nature
vol.514 pp.620-623
(Article)
Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes
Sofia Fortunato, Marcin Adamski, Sven Leininger, Jing Liu, David Ellard Keith Ferrier, Maja Adamska 
2013 (6)
BMC Biology
vol.11 
(Review article)
2010 (22/11)
Proceedings of the Royal Society B: Biological Sciences
vol.277 pp.3381-3389
(Article)
Ancient homeobox gene loss and the evolution of chordate brain and pharynx development
Thomas Butts, Peter W.H. Holland, David Ellard Keith Ferrier 

Contact

The Secretary
Scottish Oceans Institute
Institiud Chuantan na h-Alba
Gatty Marine Laboratory
East Sands St Andrews
KY16 8LB
Scotland
UK

tel: +44 (0) 1334 463472
fax: +44 (0) 1334 463443
email: soi@st-andrews.ac.uk

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